serological evidence and sociodemographic risk factors of recent cytomegalovirus infection in pregnant women attending a tertiary hospital in maiduguri, nigeria
نویسندگان
چکیده
introduction : human cytomegalovirus (hcmv) is able to go into latency and is the most common cause of congenital infections in humans. its clinical manifestations range from asymptomatic forms to severe fetal damage, and in rare cases, fetal death due to abortion. this prospective cross-sectional study was designed to determine the seroprevalence of hcmv infection in pregnant women attending antenatal clinics of the university of maiduguri teaching hospital, nigeria, and to identify its possible risk factors. methods: blood samples were collected from 182 pregnant women aged 16 to 40 years. samples were tested for anti-cmv specific igg and igm antibodies using the commercial elisa kits. a brief structured questionnaire was used to obtain some of their sociodemographic characteristics. results: seroprevalence of cmv-specific igg and igm were 79.1% and 2.2%, respectively. of 182 women, 144 had previous exposure to cmv [igg (+) igm (-)], 3 had cmv reactivated infection [igg (+) igm (+)], 37 were susceptible to cmv [igg (-) igm (-)], and only one woman had recent infection [igg (-) igm (+)]. there was no significant association between seroprevalence and any of the studied sociodemographic data (p>0.05). conclusion: the findings of this study indicated that a large number of the studied pregnant women were non-immune (susceptible) to hcmv infection, while four of them had active hcmv infection, which places their unborn children at risk of acquiring congenital hcmv infections. therefore, it is necessary to screen pregnant women for cmv infection as part of their antenatal care and follow-up them to assess the effect that cmv might have on their fetuses. j med microbiol infec dis, 2014, 2 (2): 7 pages.
منابع مشابه
Serological Evidence and Sociodemographic Risk Factors of Recent Cytomegalovirus Infection in Pregnant Women Attending a Tertiary Hospital in Maiduguri, Nigeria
Introduction : Human cytomegalovirus (HCMV) is able to go into latency and is the most common cause of congenital infections in humans. Its clinical manifestations range from asymptomatic forms to severe fetal damage, and in rare cases, fetal death due to abortion. This prospective cross-sectional study was designed to determine the seroprevalence of HCMV infection in pregnant women attending...
متن کاملSerological Evidence and Sociodemographic Risk Factors of Recent Cytomegalovirus Infection in Pregnant Women Attending a Tertiary Hospital in Maiduguri, Nigeria
Human cytomegalovirus (HCMV) belongs to the family Herpesviridae, which its members are able to remain latent in various cells of the human body for a long time [1]. Globally, CMV is a very common viral infection and one of the most common causes of congenital infections. There are some evidences indicating that CMV infection leads to miscarriage and stillbirth [2]. Even in infants who are asym...
متن کاملSerological Evidence and Associated Risk Factors for Toxoplasma gondii in Gorgan and a Review of Recent Studies in Golestan Province
Background and purpose: Toxoplasma gondii is one of the most common parasitic infections in humans and other vertebrates worldwide. This study aimed at determining the seroprevalence of Toxoplasma infection and associated risk factors in individuals attending a Reference Laboratory in Gorgan, Iran. Moreover, recent studies in Golestan province were reviewed. Materials and methods: A descriptiv...
متن کاملprevalence, sociodemographic characteristics and risk factors for hepatitis c infection among pregnant women in calabar municipality, nigeria
متن کامل
Ectopic pregnancy. Prevalence and risk factors in women attending a tertiary care hospital in Saudi Arabia.
OBJECTIVES To find the prevalence, risk factors, and pattern of management of ectopic pregnancy (EP). METHODS This retrospective study was conducted between January 2000 and December 2010 in all patients admitted to King Fahd Hospital of University, Al-Khobar, Kingdom of Saudi Arabia. Patients with suspected history of EP were collected. We collected the following data: age, parity, history o...
متن کاملPrevalence, Sociodemographic Characteristics and Risk Factors for Hepatitis C Infection among Pregnant Women in Calabar Municipality, Nigeria
BACKGROUND AND AIMS The epidemiology and risk factors for hepatitis C virus (HCV) infection in developing countries where intravenous drug use (IDU) is uncommon its poorly understood. This study therefore aims to determine the prevalence of HCV and its associated risk factors among pregnant women in Calabar municipality. METHODS A total of 506 out of 716 antenatal care (ANC) patients seen at ...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
journal of medical microbiology and infectious diseasesجلد ۲، شماره ۲، صفحات ۴۹-۵۵
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023